A01-4 田村 朋則（京都大学大学院 工学研究科）

A01-4 田村 朋則（京都大学大学院 工学研究科）

  1. T. Tamura, M. Takato, K. Shiono, I. Hamachi: “Development of a Photoactivatable Proximity Labeling Method for the Identification of Nuclear Proteins” Chem. Lett., 49, 145–148 (2020) DOI: https://doi.org/10.1246/cl.190804
  2. T. Ueda, T. Tamura, I. Hamachi: “Development of a Cell-based Ligand-screening System for Identifying Hsp90 Inhibitors” Biochemistry, 59, 2, 179–182 (2020) DOI: https://doi.org/10.1021/acs.biochem.9b00781
  3. Y. Nishikawa, T. Miki, M. Awa, K. Kuwata, T. Tamura, I. Hamachi: “Development of a Nitric oxide-responsive Labeling Reagent for Proteome Analysis of Lve Cells” ACS Chem. Biol., 14, 397–404(2019) DOI: https://doi.org/10.1021/acschembio.8b01021
  4. N. Shindo, H. Fuchida, M. Sato, K. Watari, T. Shibata, K. Kuwata, C. Miura, K. Okamoto, Y. Hatsuyama, K. Tokunaga, S. Sakamoto, S. Morimoto, Y. Abe, M. Shiroishi, J. M. M. Caaveiro, T. Ueda, T. Tamura, N. Matsunaga, T. Nakao, S. Koyanagi, S. Ohdo, Y. Yamaguchi, I. Hamachi, M. Ono, A. Ojida: “Selective and Reversible Modification of Kinase Cysteines with Chlorofluoroacetamides” Nat. Chem. Biol., 15, 250–258(2019) DOI: https://doi.org/10.1038/s41589-018-0204-3
  5. T. Tamura, A. Fujisawa, M. Tsuchiya, Y. Shen, K. Nagao, S. Kawano, Y. Tamura, T. Endo, M. Umeda, I. Hamachi: “Organelle Membrane-specific Chemical Labeling and Dynamic Imaging in Living Cells” Nat. Chem. Biol., 16, 1361-1367 (2020) DOI: https://doi.org/10.1038/s41589-020-00651-z
  6. H. Zhu, T. Tamura, A. Fujisawa, Y. Nishikawa, R. Cheng, M. Takato, I. Hamachi: “Imaging and Profiling of Proteins under Oxidative Conditions in Cells and Tissues by Hydrogen-peroxide-responsive Labeling” J. Am. Chem. Soc., 142, 15711–15721 (2020) DOI: https://doi.org/10.1021/jacs.0c02547
  7. V. Thimaradka, J. H. Oh, C. Heroven, A. R. Aricescu, M. Yuzaki, T. Tamura, I. Hamachi: “Site-specific covalent labeling of His-tag fused proteins with N-acyl-N-alkyl sulfonamide reagent” Bioorg. Medi. Chem., 30, 115947(2021) DOI: https://doi.org/10.1016/j.bmc.2020.115947
  8. T. Ueda, T. Tamura, M. Kawano, K. Shiono, F. Hobor, A. J. Wilson, I. Hamachi: “Enhanced Suppression of a Protein–Protein Interaction in Cells Using Small-Molecule Covalent Inhibitors Based on an N-Acyl-N-alkyl Sulfonamide Warhead” J. Am. Chem. Soc., 143, 4766–4774(2021) DOI: https://doi.org/10.1021/jacs.1c00703
  9. S. Watari, H. Inaba, T. Tamura, A. M. R. Kabir, A. Kakugo, K. Sada, I. Hamachi, K. Matsuura: “Light-induced Stabilization of Microtubules by Photo-crosslinking of Tau-derived Peptide” Chem. Comm., 58, 9190-9193 (2022) DOI: https://doi.org/10.1039/D2CC01890J
  10. H. Nonaka, T. Mino, S. Sakamoto, J. H. Oh, Y. Watanabe, M. Ishikawa, A. Tsushima, K. Amaike, S. Kiyonaka, T. Tamura, A. R. Aricescu, W. Kakegawa, E. Miura, M. Yuzaki, I. Hamachi: “Revisiting PFA-mediated Tissue Fixation Chemistry: FixEL Enables Trapping of Small Molecules in the Brain to Visualize Their Distribution Changes” Chem., 9, 523-540 (2023) DOI: https://doi.org/10.1016/j.chempr.2022.11.005
  11. M. Tsuchiya, N. Tachibana, K. Nagao, T. Tamura, I. Hamachi: “Organelle-selective Click Labeling Coupled with Flow Cytometry Allows Pooled CRISPR Screening of Genes Involved in Phosphatidylcholine Metabolism” Cell Metab., 35, 1072–1083 (2023) DOI: https://doi.org/10.1016/j.cmet.2023.02.014
  12. V. Thimaradka, H. Utsunomiya, T. Tamura, I. Hamachi: “Endogenous Cell-surface Receptor Modification by Metal Chelation-assisted Pyridinium Oxime Catalyst” Org. Lett., 25, 2118–2122 (2023) DOI: https://doi.org/10.1021/acs.orglett.3c00541
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