A02-1 古川 良明（慶應義塾大学 理工学部）

A02-1 古川 良明（慶應義塾大学 理工学部）

  1. G. Tanaka, T. Yamanaka, Y. Furukawa, N. Kajimura, K. Mitsuoka, N. Nukina: “Sequence- and Seed-structure-dependent Polymorphic Fibrils of Alpha-synuclein” Biochim. Biophys. Acta 1865, 1410-1420 (2019) DOI: https://doi.org/10.1016/j.bbadis.2019.02.013
  2. 【領域内連携】E. Tokuda, Y. Takei, S. Ohara, N. Fujiwara, I. Hozumi, Y. Furukawa: “Wild-type Cu/Zn-Superoxide Dismutase is Misfolded in Cerebrospinal Fluid of Sporadic Amyotrophic Lateral Sclerosis” Mol. Neurodegener. 14 42 (2019) DOI: https://doi.org/10.1186/s13024-019-0341-5
  3. I. Anzai, E. Tokuda, S. Handa, H. Misawa, S. Akiyama, Y. Furukawa: “Oxidative Misfolding of Cu/Zn-Superoxide Dismutase Triggered by Non-canonical Intramolecular Disulfide Formation” Free Radic. Biol. Med. 9, 18697-18702 (2019) DOI: https://doi.org/10.1039/c9ra02872b
  4. M. Hirose, M. Asano, S. Watanabe-Matsumoto, K. Yamanaka, Y. Abe, M. Yasui, E. Tokuda, Y. Furukawa, H. Misawa: “Stagnation of Glymphatic Interstitial Fluid Flow and Delay in Waste Clearance in the SOD1-G93A Mouse Model of ALS” Neurosci. Res. (2021) 171, 74-82 DOI: https://doi.org/10.1016/j.neures.2020.10.006
  5. Y. Furukawa, A. Shintani, T. Kokubo: “A Dual Role of Cysteine Residues in the Maturation of Prokaryotic Cu/Zn-Superoxide Dismutase” Metallomics, 13, mfab050 (2021) DOI: https://doi.org/10.1093/mtomcs/mfab050
  6. S. Kimura, H. Kamishina, Y. Hirata, K. Furuta, Y. Furukawa, O. Yamato, S. Maeda, Y. O. Kamatari: “Novel Oxindole Compounds Inhibit the Aggregation of Amyloidogenic Proteins Associated with Neurodegenerative Diseases” Biochim. Biophys. Acta, 1866, 130114 (2022) DOI: https://doi.org/10.1016/j.bbagen.2022.130114
  7. 【領域内連携】M. Tajiri, H. Aoki, A. Shintani, K. Sue, S. Akashi, Y. Furukawa: “Metal Distribution in Cu/Zn-Superoxide Dismutase Revealed by Native Mass Spectrometry” Free Radic. Biol. Med., 183, 60-68 (2022) DOI: https://doi.org/10.1016/j.freeradbiomed.2022.03.014
  8. Y. Imamura, A. Okuzumi, S. Yoshinaga, A. Hiyama, Y. Furukawa, T. Miyasaka, N. Hattori, N. Nukina: “Quantum-dot-labeled Synuclein Seed Assay Identifies Drugs Modulating the Experimental Prion-like Transmission” Commun. Biol., 5, 636 (2022) DOI: https://doi.org/10.1038/s42003-022-03590-8
  9. H. Moriyama, G. Ogata, H. Nashimoto, S. Sawamura, Y. Furukawa, H. Hibino, H. Kusuhara, Y. Einaga: “A Rapid and Simple Electrochemical Detection of the Free Drug Concentration in Human Serum Using Boron-doped Diamond Electrodes” Analyst, 147, 4442-4449 (2022) DOI: https://doi.org/10.1039/D2AN01037B
  10. Y. Fujino, M. Ueyama, T. Ishiguro, D. Ozawa, H. Ito, T. Sugiki, A. Murata, A. Ishiguro, T. Gendron, K. Mori, E. Tokuda, T. Taminato, T. Konno, A. Koyama, Y. Kawabe, T. Takeuchi, Y. Furukawa, T. Fujiwara, M. Ikeda, T. Mizuno, H. Mochizuki, H. Mizusawa, K. Wada, K. Ishikawa, O. Onodera, K. Nakatani, L. Petrucelli, H. Taguchi, Y. Nagai “FUS Regulates RAN Translation through Modulating the G-quadruplex Structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD” eLife, 12, RP84338 (2023) DOI: https://doi.org/10.7554/eLife.84338
  11. Y. Furukawa, K. Matsumoto, K. Nakagome, A. Shintani, K. Sue: “Zinc-mediated Interaction of Copper Chaperones through Their Heavy-Metal Associated Domains” J. Trace Elem. Med. Biol., 75, 127111 (2023) DOI: https://doi.org/10.1016/j.jtemb.2022.127111
  12. K. Hashimoto, S. Watanabe, M. Akutsu, N. Muraki, H. Kamishina, Y. Furukawa, K. Yamanaka: “Intrinsic Structural Vulnerability in the Hydrophobic Core Induces Species-specific Aggregation of Canine SOD1 with Degenerative Myelopathy-linked E40K Mutation” J. Biol. Chem., 299, 104798 (2023) DOI: https://doi.org/10.1016/j.jbc.2023.104798
  13. Y. Furukawa, A. Shintani, S. Narikiyo, K. Sue, M. Akutsu, N. Muraki: “Characterization of a Novel Cysteine-less Cu/Zn-superoxide dismutase in Paenibacillus lautus Missing a Conserved Disulfide Bond” J. Biol. Chem., 299, 105040 (2023) DOI: https://doi.org/10.1016/j.jbc.2023.105040
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