A02-K02 豊國 伸哉(名古屋大学大学院 医学系研究科)

A02-K02 豊國 伸哉(名古屋大学大学院 医学系研究科)

  1. Y. Okazaki, N. Misawa, S. Akatsuka, N. Kohyama, Y.Sekido, T. Takahashi, S. Toyokuni: “Frequent homozygous deletion of Cdkn2a/2b in tremolite-induced malignant mesothelioma in rats. Cancer Sci. 111, 1180-1192 (2020) DOI: https://doi.org/10.1111/cas.14358
  2. S. Akatsuka, G. H. Li, S. Kawaguchi, T. Takahashi, M. Yoshihara, M. Suyama, S. Toyokuni: “Augmented Oxidative Stress Increases 8-Oxoguanine Preferentially in the Transcriptionally Active Genomic Regions” Free Radic. Res. 54, 872-882 (2021) DOI: https://doi.org/10.1080/10715762.2020.1733548
  3. S. Funahashi, Y. Okazaki, S. Akatsuka, T. Takahashi, K. Sakumi, Y. Nakabeppu, S. Toyokuni: “Mth1 Deficiency Provides Longer Survival upon Intraperitoneal Crocidolite Injection in Female Mice. Free Radic. Res. 54, 195-205 (2020) DOI: https://doi.org/10.1080/10715762.2020.1743285
  4. Y. Okazaki Y, S.H. Chew, H. Nagai, Y. Yamashita, H. Ohara, L. Jiang, S. Akatsuka, T. Takahashi, S. Toyokuni: “Overexpression of miR-199/214 is a Distinctive Feature of Iron- and Asbestos-induced Sarcomatoid Mesothelioma in Rats” Cancer Sci. 111, 2016-2027 (2020) DOI: https://doi.org/10.1111/cas.14405
  5. F. Ito, I. Yanatori, Y. Maeda, K. Nimura, S. Ito, T. Hirayama, H. Nagasawa, N. Kohyama, Y. Okazaki, S. Akatsuka, S. Toyokuni: “Asbestos Conceives Fe(II)-dependent Mutagenic Stromal Milieu through Ceaseless Macrophage Ferroptosis and β-catenin Induction in Mesothelium” Redox Biol. 36, 101616 (2020) DOI: https://doi.org/10.1016/j.redox2020.101616
  6. S. Hayashi, T. Nakamura, Y. Motooka, F. Ito, L. Jiang, S. Akatsuka, A. Iwase, H. Kajiyama, F. Kikkawa, S. Toyokuni: “Novel Ovarian Endometriosis Model Causes Infertility via Iron-mediated Oxidative Stress in Mice” Redox Biol. 37, 101726 (2020) DOI: https://doi.org/10.1016/j.redox.2020.101726
  7. L. Jiang, H. Zheng, Q. Lyu, S. Hayashi, K. Sato, Y. Sekido, K. Nakamura, H. Tanaka, K. Ishikawa, H. Kajiyama, M. Mizuno, M. Hori, S. Toyokuni: “Lysosomal Nitric Oxide Determines Transition from Autophagy to Ferroptosis after Exposure to Plasma-activated Ringer’s Lactate” Redox Biol. 43, 101989, (2021) DOI: https://doi.org/10.1016/j.redox.2021.101989
  8. I. Yanatori, R. D. Richardson, H. S. Dhekne, S. Toyokuni, F. Kishi: “CD63 is Regulated by Iron via the IRE-IRP System and is Important for Ferritin Secretion by Extracellular Signals” Blood 138, 1490-1503 (2021) DOI: https://doi.org/10.1182/blood.2021010995
  9. F. Ito, K. Kato, I. Yanatori, T. Murohara, S. Toyokuni: “Ferroptosis-dependent Extracellular Vesicles from Macrophage Contribute to Asbestos-induced Mesothelial Carcinogenesis through Loading Ferritin” Redox Biol. 47, 102174 (2021) DOI: https://doi.org/10.1016/j.redox.2021.102174
  10. H. Zheng, L. Jiang, T. Tsuduki, M. Conrad, S. Toyokuni: “Embryonal Erythropoiesis and Aging Exploit Ferroptosis” Redox Biol. 48, 102175, (2021) DOI: https://doi.org/10.1016/j.redox.2021.102175
  11. Z. Cheng, S. Akatsuka, G. H. Li, K. Mori, T. Takahashi, S. Toyokuni: “Ferroptosis-resistance Determines High Susceptibility of Murine A/J Strain to Iron-induced Renal Carcinogenesis” Cancer Sci. 113, 65-78 (2022) DOI: https://doi.org/10.1111/cas.15175
  12. L. Yue, Y. Luo, L. Jiang, Y. Sekido, S. Toyokuni: “PCBP2 Knockdown Promotes Ferroptosis in Malignant Mesothelioma” Pathology Internatinal 72, 242-251 (2022) DOI: https://doi.org/10.1111/pin.13209
  13. Y. Kong, S. Akatsuka, Y. Motooka, H. Zheng, Z. Cheng, Y. Shiraki, T. Mashimo, T. Imaoka, S. Toyokuni: “BRCA1 Haploinsufficiency Promotes Chromosomal Amplification under Fenton Reaction-based Carcinogenesis through Ferroptosis-resistance” Redox Biol. 54, 1023562022 (2022) DOI: https://doi.org/10.1016/j.redox.2022.102356
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